Hasan, who divorced Ayla after her disgrace, decides to leave the hospital with Zeynep. They go to another hospital where they can work together and be happy. A difficult process awaits the new assistants Duygu and Ahmet who take their place. Zenan takes it out on them at every opportunity for his best friend Ela's departure. Duygu, on the other hand, is late for work on her first day and her intimacy with Çiçek, the patient she is assigned to, gets her into trouble. Duygu has another surprise for everyone before the day ends. Levent tries to overcome the unhappiness caused by Ela's absence by devoting himself to his work. This time his patient is a loving young girl (Çiçek) who is attached to life, but the deadly tumor that has settled in her body makes her a little weaker every day. The solution Levent finds is very risky. And in the middle of all this chaos, the child of Kader, who used to work as a surgical assistant at the hospital, appears. İnci has marrow cancer.