Hülya Gülşen was born in Ankara on September 14, 1965. After completing middle school, she entered the Ankara State Conservatory at the age of 13 through a special exam. When the conservatory became affiliated with Hacettepe University, she graduated from both the conservatory and high school externally during the same period.

After taking on roles in various private theaters, Hülya Gülşen joined the State Theaters in 1984 and performed there continuously for 28 years. In addition to acting, the artist has also worked in areas such as voice acting, teaching, and acting coaching. Hülya Gülşen began her television career

She began her career in 1993 with the series Ferhunde Hanımlar. She gained a wide audience by playing the character Müjgan in this series. She later appeared in series such as Bizim Evin Halleri, Havada Bulut, Keşanlı Ali Destanı, Kırgın Çiçekler, and Galip Derviş.

He began his film career in 1989 with the film Freedom For a Moment. He later starred in films such as You Are My Everything, Love Loves Coincidences 2 (2020), and Private Lesson (2022).